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Clinical laboratory features of Meigs’ syndrome: a retrospective study from 2009 to 2018

Wenwen Shang, Lei Wu, Rui Xu, Xian Chen, Shasha Yao, Peijun Huang, Fang Wang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 116-124 doi: 10.1007/s11684-019-0732-6

Abstract: Meigs’ syndrome (MS), a rare complication of benign ovarian tumors, is easily misdiagnosed as ovarianSerum carbohydrate antigen 125 and HE4 levels were higher in the MS group than in the ovarian thecoma-fibroma

Keywords： Meigs’ syndrome     ovarian thecoma-fibroma     NLR (neutrophil to lymphocyte ratio)     CD4+ T cells    

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Effect of repeated gonadotropin stimulation on ovarian reserves and proliferation of ovarian surface

Linlin LIANG, Bei XU, Guijin ZHU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 220-226 doi: 10.1007/s11684-009-0037-2

Abstract: This study aimed to evaluate the effect of repeated ovarian stimulation (OS) on the ovarian folliculartotal of 75 mice were enrolled in this experiment and randomly assigned into three groups: repeated ovarianIn the three groups, the single ovarian stimulation treatment significantly increased the mean numberRepeated ovarian stimulation also tended to decrease normal follicles of primary follicles (66.67%) andIn conclusion, single ovarian stimulation may produce more oocytes/embryos.

Keywords： gonadotropin-releasing hormone     ovarian reserve     embryo developmental ability     ovarian surface epithelium    

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Methodologies for the establishment of an orthotopic transplantation model of ovarian cancer in mice

Cunjian Yi, Lei Zhang, Fayun Zhang, Li Li, Shengrong Ling, Xiaowen Wang, Xiangqiong Liu, Wei Liang

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 101-105 doi: 10.1007/s11684-014-0315-5

Abstract:

This study used different methods to establish an animal model of orthotopic transplantation for ovarianThis study successfully established an orthotopic transplantation model of ovarian cancer with high ratesThis study also provided a methodological basis for future establishment of an animal model of ovarian

Keywords： ovarian cancer     orthotopic transplantation     animal model    

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Clinical outcomes and prognostic factors of patients with epithelial ovarian cancer subjected to first-line

Yunfeng Fu, Xinyu Wang, Zimin Pan, Xing Xie

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 91-95 doi: 10.1007/s11684-014-0305-7

Abstract:

A total of 251 patients with epithelial ovarian cancer (EOC) treated between 2002 and 2008 was retrospectively

Keywords： ovarian carcinoma     prognostic factors     surgery     chemotherapy     survival    

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Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer

Xianxian Li, Hui Xing, Lin Li, Yanli Huang, Min Zhou, Qiong Liu, Xiaomin Qin, Min He

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 96-100 doi: 10.1007/s11684-014-0316-4

Abstract:

Lymph node metastasis has an important effect on prognosis of patients with ovarian cancer.Analysis of the correlation between PAN clearance and prognosis in epithelial ovarian cancer was conductedConsequently, in ovarian carcinoma cytoreductive surgery, resection of the para-aortic lymph node, whichhas an important function in clinical treatment and prognosis of patients with ovarian cancer, is necessary

Keywords： ovarian cancer     para-aortic lymph node     pelvic lymph node    

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Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer

Bo Zhou, Hongbin Xu, Meng Xia, Chaoyang Sun, Na Li, Ensong Guo, Lili Guo, Wanying Shan, Hao Lu, Yifan Wu, Yuan Li, Degui Yang, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen, Kezhen Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 214-222 doi: 10.1007/s11684-017-0518-7

Abstract: Dysfunctional miR-9 expression remains ambiguous, and no consensus on the metastatic progression of ovarianresults confirmed that miR-9 could directly target this 3′-UTR. miR-9 and E-cadherin expression in ovarianThe results showed that miR-9 was frequently upregulated in metastatic serous ovarian cancer tissue comparedThus, our study demonstrates that miR-9 may promote ovarian cancer metastasis via targeting E-cadherinand a novel potential therapeutic approach to control metastasis of ovarian cancer.

Keywords： ovarian cancer     metastasis     miR-9     E-cadherin    

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Possibility of women treated with fertility-sparing surgery for non-epithelial ovarian tumors to safely

Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 509-517 doi: 10.1007/s11684-017-0554-3

Abstract: outcomes of childbearing-age women treated with fertility-sparing surgery (FSS) for non-epithelial ovarianOne hundred and forty eight non-epithelial ovarian tumor women treated with FSS between January 1, 2000Non-epithelial ovarian tumors can achieve fulfilling prognosis after FSS and chemotherapy.

Keywords： malignant germ cell tumors     ovarian sex cord-stromal tumors     fertility-sparing surgery     prognosis     fertility    

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Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the

Frontiers of Medicine   Pages 924-938 doi: 10.1007/s11684-023-1004-z

Abstract: However, the potential mechanism by which lncRNAs affect the recurrence and metastasis of ovarian cancerIn the current study, the lncRNA LOC646029 was markedly downregulated in metastatic ovarian tumors comparedloss-of-function assays demonstrated that LOC646029 inhibits the proliferation, invasiveness, and metastasis of ovarianMoreover, the downregulation of LOC646029 in metastatic ovarian tumors was strongly correlated with poorCollectively, our results demonstrated that LOC646029 is involved in the progression and metastasis of ovarian

Keywords： ovarian cancer     lncRNA LOC646029     metastasis     microRNA 627-3p     SPRED1    

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Paratesticular fibrous pseudotumor: a report of five cases and literature review

Zhicheng Zhang,Jun Yang,Mingchao Li,Wei Cai,Qingquan Liu,Tao Wang,Xiaolin Guo,Shaogang Wang,Jihong Liu,Zhangqun Ye

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 484-488 doi: 10.1007/s11684-014-0325-3

Abstract:

Paratesticular fibrous pseudotumor is a rare benign tumor that originates from intrascrotal tissue, such as tunica vaginalis, epididymis, or spermatic cord. Five cases of fibrous pseudotumor in our hospital were reviewed retrospectively, and the clinical manifestations were analyzed. Three cases of unilateral nodules, comprising one case located in the tunica vaginalis and two cases located in the epididymis, underwent local excision of the unilateral nodule. Two cases of diffuse incrassation in the tunica vaginalis underwent right radical orchiectomy. Postoperative pathological examination showed that all were fibrous pseudotumors. An average follow-up of 26 months showed uneventful results without recurrence for all patients. Fibrous pseudotumor is not a neoplasm but a reactive fibrous inflammatory hyperplasia. Definitive diagnosis requires pathological examination. Radical orchiectomy should be avoided when possible, and local excision should be performed because of the lack of obvious evidence of potential malignancy.

Keywords： fibroma     inflammation     scrotum     testicular neoplasm    

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Pituitary-ovarian hormone and follicular development of various combined oral contraceptives regimens

Huang Pei,Huang Xunbin

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 16-20

Abstract: The primary mode of action for COCs is thought to be suppression of the pituitary-ovarian axis by higherprogestin, secondarily leading to suppression of endogenous gonadotropin and gonadal hormone secretion and ovarianDuring the hormone-free interval (HFI), COCs users experience activation of their pituitary–ovarian

Keywords： COCs     HFI     hormone     follicle    

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Title Author Date Type Operation

Clinical laboratory features of Meigs’ syndrome: a retrospective study from 2009 to 2018

Wenwen Shang, Lei Wu, Rui Xu, Xian Chen, Shasha Yao, Peijun Huang, Fang Wang

Journal Article

Effect of repeated gonadotropin stimulation on ovarian reserves and proliferation of ovarian surface

Linlin LIANG, Bei XU, Guijin ZHU

Journal Article

Methodologies for the establishment of an orthotopic transplantation model of ovarian cancer in mice

Cunjian Yi, Lei Zhang, Fayun Zhang, Li Li, Shengrong Ling, Xiaowen Wang, Xiangqiong Liu, Wei Liang

Journal Article

Clinical outcomes and prognostic factors of patients with epithelial ovarian cancer subjected to first-line

Yunfeng Fu, Xinyu Wang, Zimin Pan, Xing Xie

Journal Article

Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer

Xianxian Li, Hui Xing, Lin Li, Yanli Huang, Min Zhou, Qiong Liu, Xiaomin Qin, Min He

Journal Article

Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer

Bo Zhou, Hongbin Xu, Meng Xia, Chaoyang Sun, Na Li, Ensong Guo, Lili Guo, Wanying Shan, Hao Lu, Yifan Wu, Yuan Li, Degui Yang, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen, Kezhen Li

Journal Article

Possibility of women treated with fertility-sparing surgery for non-epithelial ovarian tumors to safely

Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li

Journal Article

Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the

Journal Article

Paratesticular fibrous pseudotumor: a report of five cases and literature review

Zhicheng Zhang,Jun Yang,Mingchao Li,Wei Cai,Qingquan Liu,Tao Wang,Xiaolin Guo,Shaogang Wang,Jihong Liu,Zhangqun Ye

Journal Article

Pituitary-ovarian hormone and follicular development of various combined oral contraceptives regimens

Huang Pei,Huang Xunbin

Journal Article